Search results for "Cancer-related anaemia"

Erythropoietin: effects on life expectancy in patients with cancer-related anaemia

2006

ABSTRACTAnaemia is common in patients with cancer and has a detrimental impact on the quality of life. Anaemia has also been shown to reduce survival in patients with cancer. Tumour hypoxia resulting from the reduced oxygen carrying capacity of the blood in anaemic patients has been hypothesised to be a major contributor to this reduced survival. Several studies have shown that tumour hypoxia reduces the effectiveness of anticancer therapies including standard radiotherapy and some types of chemotherapy, and is associated with tumour progression. Moreover, preclinical data have demonstrated that erythropoietic protein therapy may delay tumour progression by improving tumour oxygenation. Mos…